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Radiopharmaceutical Chemistry

Course Requirements

While actual schedules will be individualized for each Fellow (e.g., courses in Biochemistry or Medical Physics with appropriate pre-requisites or instructor permission), a typical coursework schedule for the inorganic and organic tracks would be:

Fellows may audit additional courses of interest or when determined important for a broad interdisciplinary scope. Some possible research topics include:

  • Synthesis and characterization of new radiolabeled receptor-avid peptides
  • Development of new bifunctional chelating agents for radiolabeling biomolecules
  • Development of production and separation procedure for radiolanthanides
  • Antisense imaging of non-Hodgkin’s lymphoma and other cancers
  • Lanthanide radiopharmaceuticals for pretargeted Radioimmunotherapy of carcinomas
  • Unusual tumor cell killing mechanisms of copper radiopharmaceuticals
  • Radiometal-cyclized somatostatin analogues for tumor imaging therapy
  • Nanoscience and nanotechnology in nanomedicine
  • Design of main group ligands as complexing agents to metallic radioisotopes/development of site-specific radiopharmaceuticals
  • Technetium/rhenium(I) conjugates of bombesin: potential radiotracers targeting the gastrin releasing peptide receptor
  • Development of novel melanoma imaging and radiotherapy approaches
  • Opioid receptor targeting
  • Structure affinity relationships of sigma ligands
  • Development of radiotracers for visualizing the molecular targets of addictive drugs in the human brain
  • Development of radiotracers for imaging aromatase activity
  • Development of muscarinic receptor selective radiotracers for measure changes in endogenous acetylcholine
  • Synthesis of alpha-7 nicotinic receptor-specific radiotracers
  • Developing new radiotracers to investigate membrane status
  • Development and evaluation of new bifunctional chelating agents for targeted radiotherapy
  • Development and evaluation of chelating agents for At-211
  • Development and evaluation of new bifunctional chelating agents for targeting intracellular Fe

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